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Simply dieting or exercising after stopping semaglutide proved insufficient to maintain the weight loss achievedsuggesting that the medication's effect on appetite regulation is fundamentally different from willpower-based approaches

Diabetologia 47 , 47: 478487 (2004)

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Shortly after adding the antibody treatments at the 2-week timepoint, the two semaglutide arms continued to parallel each other in terms of body weight (Fig